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Glutaraldehyde – Health Hazards in Hospitals and Healthcare Facilities

If you need assistance with glutaraldehyde – health hazards as discussed in this article, call us at 1-800-344-4414 or e-mail us at info@atlenv.com for details and a free estimate.

Written By:  Robert E. Sheriff, MS, CIH, CSP, President
April 22, 2020

Glutaraldehyde Hazards

Glutaraldehyde is very similar to formaldehyde in its structure and uses in the healthcare industry.  Chemically, Glutaraldehyde exists at room temperature as a liquid, whereas formaldehyde exists under those conditions as a gas, which can easily be dissolved in water.

Glutaraldehyde is often used as a substitute for formaldehyde because formaldehyde is now a suspect cancer-causing substance.  Glutaraldehyde may be a good substitute for formaldehyde/formalin but it appears to be more irritating but not as toxic as formaldehyde.  Eye, throat and lung irritation has often been traced to glutaraldehyde.  Some medical schools have introduced glutaraldehyde in cadavers for student laboratories but the results have been mixed both as a tissue preservative and as an irritant.  Asthma and asthma-like symptoms have been identified by NIOSH in their investigation of hospital occurrences of the symptoms just mentioned (“Glutaraldehyde – Occupational Hazards in Hospitals”).  Contact dermatitis, hives, staining of hands (tan), and nausea are other symptoms of glutaraldehyde exposure identified by NIOSH.

An Often Used Chemical

Glutaraldehyde has many uses as a disinfectant and a tissue preservative in hospitals, labs, pharmacies, outpatient treatment centers, and of course, morgues.  It has found steady use for cold sterilization where equipment may be heat sensitive such as surgical instruments that are not totally metallic, dialysis equipment, bronchoscopes, ear, nose and throat instruments, and suction bottles.  Further, it is used as a tissue fixative for histology and pathology and in some instances, as a cadaver preservative in morgues as a substitute for formaldehyde.

Persons in hospitals and other medical-related fields who may be exposed to glutaraldehyde include:

  • Medical Students and Teachers
  • Cold Sterilization Staff
  • Operating Room Personnel
  • Dialysis Personnel
  • Intensive Care-Infection Control Staff
  • Histology Lab Technicians
  • Medical Researchers
  • Central Service and Maintenance
  • Workers who develop X-Rays
  • Mixing and diluting sterilization solutions
  • Medical examiners and staff who occupy morgues

It is relatively easy to monitor medical staff personnel and hospital departments for glutaraldehyde.  A small badge can be worn on the collar during exposure situations.  It gets much more complicated in correcting exposure problems, especially where substitute solutions are not as effective in dealing with sterilization needs.  Corrective measures and exposure controls may require the services of a specialist such as an industrial hygienist.  Controls such as downdraft tables, lab hoods, local exhaust ventilation, and respiratory protection must be considered as options.

If you need assistance in evaluating glutaraldehyde exposures or addressing control measures, contact us.

Robert E. Sheriff is the CEO of Atlantic Environmental.  A Certified Industrial Hygienist and Certified Safety Specialist, he has over thirty years of experience providing human health hazard assessments, indoor air quality assessments, and ventilation design.  For more information and a free proposal, contact him at 800-344-4414 or email him at info@atlenv.com.

For more information contact Atlantic Environmental.

Our primary service areas for Glutaraldehyde Sampling and Consulting are New Jersey NJNew York NY, (New York City)Pennsylvania PAConnecticut CTDelaware DEMassachusetts, (Boston) MARhode Island RIWashington DCWisconsin WIMaryland MDMichigan MIIllinois (Chicago) ILVirginia VAIndiana INGeorgia (Atlanta) GAAlabama ALNorth Carolina NCSouth Carolina SCTennessee TNTexas (Dallas, Ft Worth) TXOklahoma OKDCArkansas AR, Florida FL. We can service most other areas of the U.S. but with some added travel charges.

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